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SUMICHIRAL OA optical isomer separation columns, JapanColumn Selection
Selection Guide
Choose SUMICHIRAL phases by compound class, mobile-phase mode and whether inverse elution order is useful for impurity confirmation.
MIG-1 Plot No: 02, 9th Phase, KPHB Colony, Kukatpally, Hyderabad – 500085, Telangana, India
Email: sales@akiralabs.com | Tel: +91-9391852431Selection by Compound Class
Carboxylic acids / profen drugs
Start with OA-2500, OA-2500S, OA-3300 or OA-3300S depending on desired mode and elution order.
Amines / amides / amino alcohols
Consider OA-4000, OA-4100, OA-4400, OA-4500, OA-4600 and OA-4700 family phases.
Amino acids / hydroxy acids
Consider OA-5000, OA-5000L, OA-6000, OA-6000R, OA-6100 and OA-6100R ligand-exchange phases.
Aromatic isomers / host-guest separations
Consider OA-7000 and OA-7700 cyclodextrin phases or OA-8000 crown ether phase for amine recognition.
Frequently Asked Questions
How do I choose between OA-2500 and OA-3300?
OA-2500 is often considered for carboxylic acid and profen-type acidic compounds, while OA-3300 is a urea-type phase useful for profen drugs and N-protected amino acid derivatives. Screening both can improve selectivity confidence.
When should ligand exchange phases be used?
OA-5000, OA-6000 and OA-6100 are useful when analytes can participate in copper-ion ligand exchange, such as amino acids, hydroxy acids, amino alcohols and amines.
When should cyclodextrin phases be selected?
OA-7000 and OA-7700 are host-guest phases for reversed-phase separations, especially aromatic compounds and amines where cyclodextrin cavity interactions can influence recognition.